How White Blood Cells Work


|
Test
|
Name
|
Increased/decreased
|
|
White Blood Cell
|
May be
increased with infections, inflammation, cancer, leukemia; decreased
with some medications (such as methotrexate), some autoimmune conditions,
some severe infections, bone marrow failure, and congenital marrow
aplasia (marrow doesn't develop normally)
|
|
|
%
Neutrophil
|
Neutrophil/Band/Seg/Gran
|
This is
a dynamic population that varies somewhat from day to day depending on what
is going on in the body. Significant increases in particular types are
associated with different temporary/acute and/or chronic conditions. An example of this is
the increased number of lymphocytes seen with lymphocytic leukemia. For more
information, see Blood Smear and WBC.
|
|
Lymphs
|
||
|
% Mono
|
||
|
% Eos
|
||
|
% Baso
|
||
|
Neutrophil
|
Neutrophil/Ban/Seg/Gran
|
|
|
Lymphs
|
Lymphocyte
|
|
|
Mono
|
Monocyte
|
|
|
Eos
|
Eosinophil
|
|
|
Baso
|
Basophil
|
|
|
Red Blood Cell
|
||
|
Hemoglobin
|
Mirrors
RBC results
|
|
|
Hematocrit
|
Mirrors
RBC results
|
|
|
MCV
|
Mean
Corpuscular Volume
|
Increased
with B12 and Folate deficiency;
decreased with iron deficiency and thalassemia
|
|
MCH
|
Mean
Corpuscular Hemoglobin
|
Mirrors
MCV results
|
|
MCHC
|
Mean
Corpuscular Hemoglobin Concentration
|
May be
decreased when MCV is decreased; increases limited to amount of Hgb that will
fit inside a RBC
|
|
RDW
|
RBC
Distribution Width
|
Increased
RDW indicates mixed population of RBCs; immature RBCs tend to be larger
|
|
Platelet
|
Decreased or increased with conditions that affect
platelet production; decreased when greater numbers used, as with bleeding;
decreased with some inherited disorders (such as Wiskott-Aldrich,
Bernard-Soulier), with Systemic lupus erythematosus,
pernicious anemia,
hypersplenism (spleen takes too many out of circulation), leukemia, and
chemotherapy
|
|
|
MPV
|
Mean
Platelet Volume
|
Vary
with platelet production; younger platelets are larger than older ones
|
The study white blood cell in the body

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