Khmer77

Wednesday, August 5, 2015

White Blood Cell WBC

How White Blood Cells Work


Test
Name
Increased/decreased
White Blood Cell
May be increased with infections, inflammation, cancer, leukemia; decreased with some medications (such as methotrexate), some autoimmune conditions, some severe infections, bone marrow failure, and congenital marrow aplasia (marrow doesn't develop normally)
% Neutrophil
Neutrophil/Band/Seg/Gran
This is a dynamic population that varies somewhat from day to day depending on what is going on in the body.  Significant increases in particular types are associated with different temporary/acute and/or chronic conditions.  An example of this is the increased number of lymphocytes seen with lymphocytic leukemia. For more information, see Blood Smear and WBC.
Lymphs
% Mono
% Eos
% Baso
Neutrophil
Neutrophil/Ban/Seg/Gran
Lymphs
Lymphocyte
Mono
Monocyte
Eos
Eosinophil
Baso
Basophil
Red Blood Cell
Decreased with anemia; increased when too many made and with fluid loss due to diarrhea, dehydration, burns
Hemoglobin
Mirrors RBC results
Hematocrit
Mirrors RBC results
MCV
Mean Corpuscular Volume
Increased with B12 and Folate deficiency; decreased with iron deficiency and thalassemia
MCH
Mean Corpuscular Hemoglobin
Mirrors MCV results
MCHC
Mean Corpuscular Hemoglobin Concentration
May be decreased when MCV is decreased; increases limited to amount of Hgb that will fit inside a RBC
RDW
RBC Distribution Width
Increased RDW indicates mixed population of RBCs; immature RBCs tend to be larger
Platelet
Decreased or increased with conditions that affect platelet production; decreased when greater numbers used, as with bleeding; decreased with some inherited disorders (such as Wiskott-Aldrich, Bernard-Soulier), with Systemic lupus erythematosus, pernicious anemia, hypersplenism (spleen takes too many out of circulation), leukemia, and chemotherapy
MPV
Mean Platelet Volume
Vary with platelet production; younger platelets are larger than older ones


 The study white blood cell in the body


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